Assets: small peptidomimetics

IPCure is building a portfolio of first-in-class, highly selective small-molecule peptidomimetics targeting individual caspases.

Our lead program addresses Caspase-2, a pivotal regulator of synaptic function and neurodegeneration.

Compounds
DiscoveryLead opt.PreclinicalIND-enabling
Caspase-2 selective inhibitors
Casp2i Frontotemporal Dementia (FTD-Tau)
Advanced preclinical
Casp2i Alzheimer’s Disease (AD)
Preclinical
Caspases platform
Casp4i Inflammatory diseases
Exploratory
Research tools · On the market (RUO)
Casp2i™ Selective inhibitors Research Use Only (RUO)
Available now 
Casp2Sense™ Selective AMC-based Fluorogenic Substrates Research Use Only (RUO)
Available now 

Interested in joining us? Learn more inside!"

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